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COVID-19 infection, COVID-19 and blood clots, what causes blood clots in COVID-19 positive patients, health, indian express newsExcessive blood clotting in individuals with COVID-19 could also be chargeable for a number of problems arising from the infection. (Source: Pixabay)There are loads that are nonetheless to be explored, with regard to the novel coronavirus that causes COVID-19. As the healthcare sector in numerous international locations seems to be for answers as to how the physique reacts and defends itself when the virus invades it, newer prospects emerge daily. Among them is the drawback of the coronary heart, and the way it continues to operate in the presence of the viral infection.

People who’ve blood clots, virtually all the time expertise a cough and sharp ache in the chest. Clotting is certainly one of the physique’s pure responses to harm, and it happens when a number of blood modifications to a semi-solid state so as to stop extreme blood loss, says Dr. Zakia Khan, Senior Interventional Cardiologist, Fortis Hospital, Kalyan.

“Emerging evidence indicates that COVID-19 leads to blood clots in an estimated 30 percent of critically-ill patients. A blood clot (also called a thrombus), increases the risk of complications and death among those who have COVID-19. This infection causes blood clots in 20–30 percent of critically ill patients.”

Dr. Khan goes on to say that clots that type inside a deep vein might be extraordinarily harmful. These clots could not dissolve on their very own, they usually can cease the bloodstream. In some conditions, a clot can break off and journey to a different part of the physique. “This thrombus is then called an ’embolus’. If the embolus reaches the brain, heart, or lungs, it can result in a life-threatening condition, such as a heart attack or stroke.”

The doctor says that analysis suggests clotting happens when the novel coronavirus assaults the endothelial cells that line the blood vessels. “The virus does this by binding to the ACE2 receptors, which are present in the endothelial cell membrane. Once bound to the receptors, blood vessels release proteins that cause the blood to clot. Studies also indicate that COVID-19 causes the body’s immune system to trigger a hyperactive inflammatory response. This inflammation may also cause clotting. There are various other factors that may also play a role in blood clotting in people with COVID-19.”

Patients who require hospital care as a result of the infection additionally produce other threat components for blood clots, in the event that they fall beneath any of those classes:

* Being older
* Being chubby
* Having hypertension, or excessive blood strain
* Existing diabetes
* Are on medicines that improve the threat of blood clotting
* Have a historical past of coronary heart failure
* Having intervals of inactivity, resembling extended mattress relaxation
* Have undergone surgical procedure not too long ago
* Are a smoker or have a historical past of smoking
* A private or household historical past of DVT or pulmonary embolism
* Those with a blood clotting dysfunction

Complications from blood clots on the coronary heart

“Excessive blood clotting in people with COVID-19 may be responsible for several complications arising from the infection. Research indicates that people with COVID-19, who have a higher rate of blood clotting activity, are more likely to require treatment in the intensive care unit. Also, blood clots in the arteries can cause a heart attack or other cardiac issues. According to a study of 187 patients with COVID-19 at a hospital in Wuhan, 27.8 percent of the patients developed damage to the heart.”

Current and growing therapies

“Treatment includes prescribing blood-thinning medications. Many doctors begin this treatment during a person’s hospital stay and continue for 2 weeks after discharge to reduce the risk of blood clots. Taking blood thinners, however, also increase the risk of bleeding out, which may make blood thinners unsuitable for high-risk patients. There are some reports that people on mechanical ventilation with COVID-19, who took blood thinners had lower mortality than those who did not take the medication. Currently, researchers are testing new treatment options to help treat and prevent blood clots,” says Dr. Khan.

Prevention

The doctor means that the greatest method to stop an infection with the novel coronavirus is to practice good hand hygiene, put on a mask and practice bodily distancing. “People with an increased risk of blood clots should speak with their doctor. In some cases, the doctor may recommend using blood-thinning medication. However, these medications are not suitable for everyone.”

Some different methods to cut back the threat of blood clots embrace:
– Staying lively as a lot as doable
– Wearing particular stockings to enhance bloodstream
– Drinking loads of water to forestall dehydration
– Losing weight, if crucial
– Avoiding alcohol and tobacco consumption